PREVENTION OF RICKETS BY MILK FORTIFIED WITH VITAMIN D FROM COD LIVER OIL
- 2 June 1934
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 102 (22) , 1824-1831
- https://doi.org/10.1001/jama.1934.02750220002002
Abstract
The present study was undertaken for the purpose of testing the antirachitic value for infants of vitamin D concentrate from cod liver oil when it was incorporated in milk at the dairy. Though the concentrate was known to be effective in the treatment of rickets in rats,1 its efficacy in the prevention and treatment of that disorder in infants as compared with that of cod liver oil was not known. Furthermore, the investigation was considered of special value since it offered an opportunity to elaborate a method of making clinical tests of various substances that contain vitamin D, with a view to comparing their relative efficacy in the prevention of rickets in infants.2 The early studies of Barnes, Brady and James3 showed that viosterol was less effective in infants than cod liver oil when administered in a like number of rat units. Recent reports by Hess andThis publication has 1 reference indexed in Scilit:
- The determination of vitamin DBiochemical Journal, 1932