Glycosaminoglycans in patellar cartilage
- 1 January 1989
- journal article
- research article
- Published by Medical Journals Sweden AB in Acta Orthopaedica
- Vol. 60 (1) , 23-25
- https://doi.org/10.3109/17453678909150084
Abstract
We obtained samples of patellar cartilage at the time of surgery from 20 patients: 11 with normal and 9 with macroscopic cartilaginous degeneration. The glycosaminoglycans were separated by cellulose acetate electrophoresis, and the relative content of major glycosaminoglycans was measured by optic staining. The total content of glycosaminoglycans was measured by optic scanning. We found that degenerated cartilage contained an increase in dermatan sulfate and hyaluronic acid and a decrease in chondroitin 6-sulfate and total uronic acid concentration, with only slight changes in chondroitin 4-sulfate and keratan sulfate compared with normal cartilage.Keywords
This publication has 12 references indexed in Scilit:
- A new electrophoretic method for the complete separation of all known animal glycosaminoglycans in a monodimensional runAnalytical Biochemistry, 1979
- Articular cartilage, blood serum glycosaminoglycans and glycoproteins in osteoarthritis deformansClinica Chimica Acta; International Journal of Clinical Chemistry, 1979
- Biochemical changes in progressive osteoarthrosis.Annals of the Rheumatic Diseases, 1977
- Heberden Oration, 1976. Molecular approach to the understanding of osteoarthrosis.Annals of the Rheumatic Diseases, 1977
- New method for quantitative determination of uronic acidsAnalytical Biochemistry, 1973
- The Glycosaminoglycans of Normal and Arthritic CartilageJournal of Clinical Investigation, 1971
- Correlations between stiffness and the chemical constituents of cartilage on the human femoral headBiochimica et Biophysica Acta (BBA) - General Subjects, 1970
- CHONDROMALACIA OF THE PATELLAThe Journal of Bone and Joint Surgery. British volume, 1956
- Behandlung Der Epiphyseolysis Capitis Femoris Mittelst “Nagelung”Acta Orthopaedica, 1941