Dose to the Liver and Spleen in Pediatric Patients Undergoing Technetium-99m Sulfur Colloid Scans

Abstract
Quantitative conjugate view external counting techniques were applied to determine radiation dose to the liver and spleen in pediatric patients undergoing 99mTc-S colloid (Tc-SC) liver scans. The effective half-life of 99mTc-SC was 5.8 .+-. 0.23 h and 5.2 .+-. 0.68 h in the liver and spleen, respectively. Dose per administered activity was 0.34-0.63 rad/mCi (92-170 .mu.Gy[gray]/MBq[becquerel]) for the liver and 0.35-1.96 rad/mCi (95.0-530.0 .mu.Gy/MBq) for the spleen. The spleen liver dose ratio was 1.0-4.9. Results extrapolated from adults are compared with the pediatric population.

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