Statistics and Medical Experimentation
- 1 June 1975
- journal article
- clinical trial
- Published by JSTOR in Biometrics
- Vol. 31 (2) , 511-29
- https://doi.org/10.2307/2529434
Abstract
Starting from a review of four major experimental areas in medicine (Polio, Coronary Surgery, Diabetes, Breast Cancer), some of the special statistical problems arising in the design and analysis of clinical experiments are reviewed, and the limitations of current formulations are emphasized. Particular attention is given to the ethical dilemma and an alternative formulation of the inference/decision problem is proposed.Keywords
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