SUBTOTAL BILATERAL SUPRARENALECTOMY FOR HYPERSUPRARENALISM

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Abstract
Down to the present time, a study of the vasoregulatory mechanism would indicate the futility of an attempt to pick out and burden one single link of the chain and place the responsibility on this for alterations of the whole system. This does not mean, however, that a better understanding of the whole problem could not be arrived at if one of these links was studied with particular care. The heart and the peripheral vessel system must decide the issue. Both are under the regulation of nervous influences, which either act directly on the cardiac and vascular musculature and on the contractile elements of the capillary walls or are brought to bear on them indirectly through the mediation of hormones. The part played by the blood electrolytes in determining the effect of the hormone concentration is also a deciding factor. In our studies, this being a preliminary report, an attempt

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