The nuclear cycle in bacteria

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Abstract
1. Strains ofBact. coliand related bacteria possess a life cycle resembling that of Myxobacteria. The vesicular, resting nucleus is contained in a microcyst, which is formed by a process suggestive of sexual conjugation.2. The microcyst germinates by the transformation of the resting nucleus into the chromosome-like bodies typical of active, vegetative cultures. These may be analogous to the chromosome complexes of yeasts. The period of germination of microcysts corresponds to the lag phase of cultures.3. The nucleus remains permanently in the mitotic condition during the active, vegetative phase of growth, and reproduces by an asexual and a sexual method.4. Older cultures may be transformed directly into microcysts or may first adopt a secondary, vegetative phase, in which the nucleus is in the form of a single, central body.5. Microcyst formation differs from spore formation in that it lacks the obvious reduction processes associated with spore formation, upon which a few original observations are included.
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