Biologic Evaluation of a Silver-Copper-Germanium Dental Casting Alloy and a Gold-Germanium Coating Alloy
- 1 August 1983
- journal article
- research article
- Published by SAGE Publications in Journal of Dental Research
- Vol. 62 (8) , 899-903
- https://doi.org/10.1177/00220345830620081001
Abstract
An Ag-Cu-Ge alloy and an Au-Ge alloy were evaluated for their hemolytic effect on rabbit blood, cytotoxicity to α-L fibrosarcoma cells, and allergenic effect on guinea pigs. Neither alloy evoked a significant hemolytic response; cytotoxicity, and that of pure germanium, was no greater than that of ZOE cement; and, on the basis of the guinea pig response, the potential human allergenic response was considered to be Grade I (weak) and Grade II (mild), respectively.This publication has 6 references indexed in Scilit:
- Biological testing of dental restorative materials in vitro—a reviewJournal of Oral Rehabilitation, 1979
- Effects of cell concentration and exogenous prostaglandin on the interaction and responsiveness of human peripheral blood leukocytesClinical Immunology and Immunopathology, 1979
- Toxicological Evaluation of Biomaterials: Primary Acute Toxicity Screening ProgramArtificial Organs, 1977
- Cytotoxicity of temporary crown and bridge materialsJournal of Oral Rehabilitation, 1976
- Kinetic and quantitative evaluation of material cytotoxicity in vitroOral Surgery, Oral Medicine, Oral Pathology, 1973
- The Identification of Contact Allergens by Animal Assay. the Guinea Pig Maximization Test**From the Department of Dermatology, University of Gothenburg, Sahlgrenska Sjukhuset, Gothenburg, Sweden and the Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104.Journal of Investigative Dermatology, 1969