Desflurane Hepatitis Associated with Hapten and Autoantigen-Specific IgG4 Antibodies

Abstract
BACKGROUND:Three cases of drug-induced liver injury (DILI) have been reported after desflurane anesthesia. However, no previous reports have detected serum autoantibodies such as that reported with DILI from halothane or isoflurane.METHODS AND RESULTS:We describe the first documentation of cytochrom