Guanylate Kinase in Man – Multiple Molecular Forms

Abstract
A method is described for demonstration of guanylate kinase isoenzymes. In the human organism there are seven different isoenzymes, and there are distinct differences in component pattern among the various tissues. The molecular weights of the components are 25,000 or 31,000. The data presented may indicate that in man there are more than one genetic locus determining guanylate kinase. In red cell hemolysates of 385 individuals, no variation in guanylate kinase component pattern was observed.

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