Decreased Gelatin-Binding Fibronectin in Patients with Chronic Inflammatory Bowel Diseases
- 1 January 1985
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Gastroenterology
- Vol. 20 (9) , 1062-1064
- https://doi.org/10.3109/00365528509088872
Abstract
The plasma fibronectin concentration (PF) was measured in 48 patients with chronic inflammatory bowel disease (CIBD) and in 48 age- and sex-matched healthy controls, using electroimmunoassay and a functional (gelatin-binding) assay. Whereas no difference in immunochemically measured PF was found between the two groups, patients with CIBD had significantly lower gelatin-binding PF than healthy controls (p < 0.001). Immunochemically measured PF increased, whereas functionally measured PF tended to decrease with increasing disease activity.Keywords
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