Thiamin-catalyzed decarboxylation of pyruvate. Synthesis and reactivity analysis of the central, elusive intermediate, .alpha.-lactylthiamin
- 1 February 1981
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 103 (4) , 884-888
- https://doi.org/10.1021/ja00394a027
Abstract
No abstract availableThis publication has 9 references indexed in Scilit:
- Phosphonate analogues of pyruvate. Probes of substrate binding to pyruvate oxidase and other thiamin pyrophosphate-dependent decarboxylasesBiochimica et Biophysica Acta (BBA) - Enzymology, 1980
- Hydrolysis of the thiazolium ion ring of 1'-methylthiaminium ion. Rate and equilibrium constantsThe Journal of Organic Chemistry, 1980
- Reduction of the syn-anti glycosyl conformational barrier in 2'-deoxyadenosine upon binding to ethidium bromide. Evidence from ultrasonic relaxation measurementsJournal of the American Chemical Society, 1980
- Chemical synthesis of a proposed enzyme-generated "reactive intermediate analog" derived from thiamin diphosphate. Self-activation of pyruvate dehydrogenase by conversion of the analog to its componentsJournal of the American Chemical Society, 1979
- N1'-Methylthiaminium diiodide. Model study on the effect of a coenzyme bound positive charge on reaction mechanisms requiring thiamin pyrophosphateJournal of the American Chemical Society, 1978
- Carbon kinetic isotope effects on pyruvate decarboxylation catalyzed by yeast pyruvate decarboxylase and modelsJournal of the American Chemical Society, 1978
- The protonation site of vitamin B1 as determined from natural-abundance nitrogen-15 nuclear magnetic resonance spectraJournal of the American Chemical Society, 1977
- Carbon isotope effect on the enzymatic decarboxylation of pyruvic acidBiochemical and Biophysical Research Communications, 1976
- The Natural Occurrence and Enzymatic Formation of a Hydroxyethyl Derivative of Thiamine PyrophosphateJournal of Biological Chemistry, 1960