A large particle associated with the perimeter of the nuclear pore complex.
Open Access
- 1 April 1982
- journal article
- research article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 93 (1) , 63-75
- https://doi.org/10.1083/jcb.93.1.63
Abstract
The 3-dimensional structure of the nuclear pore complex was determined to a resolution of -90 .ANG. by EM using nuclear envelopes from Xenopus laevis oocytes. It is shown to be an assembly of several discrete constituents arranged with octagonal symmetry about a central axis. There are apparent 2-fold axes perpendicular to the octad axis which suggest that the framework of the pore complex is constructed from 2 equal but oppositely facing halves. The half facing the cytoplasm is in some instances decortated by large particles, similar in appearance and size to ribosomes.Keywords
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