Attenuated Live Fowl Cholera Vaccine III. Laboratory and Field Vaccination Trials in Turkeys and Chickens

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Abstract
Administered via the drinking water, M-3-G, an attenuated strain of Pasteurella multocida of serotype 1, immunized turkeys and chickens against fowl cholera. Immunity was tested by challenging birds i.m., by palatine cleft swab or orally after 3 vaccinations. No reactions to vaccination were noted in 390 turkeys in 12 laboratory trials, nor in 20,245 vaccinated in field trials. Chickens showed no vaccination reactions, and immunity was elicited by challenge in a laboratory trial and in face of natural outbreaks in the field, where 11,600 chickens were vaccinated. No vaccination reactions were noted, although most birds involved in the trials were carrying Mycoplasma spp. Immunity lasted about 10 wk after the last vacination. The immunizing properties of M-3-G are compared with the CU strain.