Infection with Herpes-Simplex Viruses 1 and 2

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Abstract
Recurrent Infection and CancerRecurrent HSV InfectionThe ability to persist in their natural host is a general property of all herpesviruses of man and nonhuman species studied to date.6,8,46 With respect to HSV-1 and HSV-2, the phenomenon itself is deceptively simple. Persons with a clear clinical record, or at least with serologic evidence, of past primary infection may exhibit recurrent* infections caused by the same virus and localized on a specific area of the body, such as the face, cornea or genitals. Descriptions and analyses of the phenomenon, as reviewed by several workers,6,46,47 reveal some very curious facets that . . .