Trypanosoma cruziin the Cerebrospinal Fluid during the Acute Stage of Chagas' Disease
- 16 March 1978
- journal article
- research article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 298 (11) , 604-606
- https://doi.org/10.1056/nejm197803162981106
Abstract
THE extent of Central-nervous-system involvement in Chagas' disease is not known.1 The only well recognized neurologic complication during the acute infection is meningoencephalitis. In patients so affected the cerebrospinal fluid contains excess protein and lymphocytes,2 and intracellular Trypanosoma cruzi can be found in the brain and in the reticular cells of the leptomeninges.3 When neurologic manifestations are absent during acute infection, the cerebrospinal fluid has been reported to be normal,4 normal except for the presence of antibody to T. cruzi, 5 or as showing elevated levels of protein and increased numbers of lymphocytes.6 In these cases direct examination revealed no T. . . .This publication has 3 references indexed in Scilit:
- The Epidemiology and Household Distribution of Seroreactivity to Trypanosoma cruzi in a Rural Community in Northeast Brazil *The American Journal of Tropical Medicine and Hygiene, 1976
- Cultivation of the Leishmaniform Stage of Trypanosoma Cruzi in Cell-Free Media at Different Temperatures *The American Journal of Tropical Medicine and Hygiene, 1968