Primary structure and transmembrane orientation of the murine anion exchange protein
- 1 July 1985
- journal article
- research article
- Published by Springer Nature in Nature
- Vol. 316 (6025) , 234-238
- https://doi.org/10.1038/316234a0
Abstract
The amino-acid sequence of murine band 3, deduced from the nucleotide sequence of a complementary DNA clone, confirms that this integral membrane glycoprotein is composed of 2 major structural domains which correlate with its dual functions as the anchor for the erythrocyte cytoskeleton and as a plasma membrane anion antiporter. This latter activity resides within a highly hydrophobic domain that crosses the plasma membrane at least 12 times.Keywords
This publication has 44 references indexed in Scilit:
- Chloride-bicarbonate exchange in red blood cells: physiology of transport and chemical modification of binding sitesPhilosophical Transactions of the Royal Society of London. B, Biological Sciences, 1982
- The Molecular Basis for Membrane – Cytoskeleton Association in Human ErythrocytesJournal of Cellular Biochemistry, 1982
- The membrane attachment protein for spectrin is associated with band 3 in human erythrocyte membranesNature, 1979
- Erythrocyte Anion Exchange and the Band 3 Protein: Transport Kinetics and Molecular StructurePublished by Elsevier ,1979
- The anion transport system of the red blood cell The role of membrane protein evaluated by the use of ‘probes’Biochimica et Biophysica Acta (BBA) - Reviews on Biomembranes, 1978
- Anion transport in relation to proteolytic dissection of band 3 proteinBiochimica et Biophysica Acta (BBA) - Biomembranes, 1978
- Classification and localization of hemoglobin binding sites on the red cell membraneBiochemistry, 1977
- Binding of rabbit muscle aldolase to band 3, the predominant polypeptide of the human erythrocyte membraneBiochemistry, 1976
- THE ORGANIZATION OF PROTEINS IN THE HUMAN RED BLOOD CELL MEMBRANEThe Journal of cell biology, 1974
- Electrophoretic analysis of the major polypeptides of the human erythrocyte membraneBiochemistry, 1971