PHYSICOCHEMICAL CHARACTERISTICS OF VIRENOMYCIN, A NEW ANTI-TUMOR ANTIBIOTIC

  • 1 January 1977
    • journal article
    • research article
    • Vol. 22  (11) , 967-970
Abstract
Virenomycin, a new crystalline antitumor antibiotic was isolated from the mycelium of Streptomyces virens. The antibiotic contained: C 64.87%, H 5.66%, methoxylic groups 9.5%. The melting temperature was 255-260.degree. C. Virenomycin had a complex UV spectrum with .lambda.max 245 (677), 265 (453), 275 (542), 287 (507), 395 (222) nm. A chromophore fragment and carbohydrate (C7H14O5) were found in the methanolysis products. Virenomycin was close to antibiotic c B-21085 in physico-chemical properties and differed from it in the character of the UV spectrum, the values of the specific absorption and by the optical rotation in dimethyl sulfoxide and acetic acid.

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