Enantioselective synthesis of homoallylic alcohols using (E)-but-2-enyl-trichlorosilane and chiral diamines

1 January 1997

journal article
research article
Published by Royal Society of Chemistry (RSC) in Chemical Communications

No. 10,p. 919-920
https://doi.org/10.1039/a701244f

Abstract

Condensation of aromatic aldehydes and (E)-but-2-enyl- trichlorosilane in the presence of (S)-(+)-4-(2-methylpropyl)-2-(2-pyridinyl)-2-oxazoline gives the corresponding homoallylic alcohols in excellent anti-diastereoselectivity (>99%) and good enantioselectivity (36–74%).

Keywords

HOMOALLYLIC ALCOHOLS
GOOD
CORRESPONDING
METHYLPROPYL
PYRIDINYL
CHIRAL
CONDENSATION
DIASTEREOSELECTIVITY

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