Effects of Acid Mucopolysaccharides on Growth Rates and Constituent Lipids of Tissue Cultures.

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Abstract
Summary Lipid analysis of chick aorta intima and HeLa cell tissue cultures confirms histological studies indicating that total lipids and cholesterol are significantly reduced per unit volume of cells when very small amounts of calf aorta extracts or the mucopolysaccharide, chondroitin sulfate A are added to the cultures. The lipid clearing effect noted in cells is often associated with stimulation of cellular growth and with a process of lipid dilution by cellular multiplication. However, in the case of one aortic extract, lipid clearing took place without significant stimulation of cellular growth. The latter suggests a specific cellular clearing effect as distinguished from lipid dilution by cell division and growth.

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