INTERRELATIONSHIP OF THE CARDIO-RESPIRATORY EVENTS IN ANOXIA
- 31 December 1949
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 160 (1) , 138-148
- https://doi.org/10.1152/ajplegacy.1949.160.1.138
Abstract
An empirical formula predicting pulmonary ventilation in dogs in 3 types of anoxia has been developed, using O2-saturation, CO2-tension, pH, and diastolic and venous blood pressures. The error involved (one root mean square deviation) in attempting a prediction of pulmonary ventilation from these measurements has been found to about 2 in 13 ventilation units, one ventilation unit being defined as the dog''s pulmonary ventilation at rest. The breathing in anoxia does not bear a linear relation to the O2-saturation, but rather the breathing is best related to the O2-saturation by means of a cubic equation. A multiple factor analysis of the dogs'' physiol. behavior in anoxia has also been made, resulting in further emphasis upon the mutual interdependence of all the measurements taken. The pH and the pCO2 appear to be 2 of many prime factors in the dogs'' over-all reactions to anoxia.Keywords
This publication has 0 references indexed in Scilit: