Absence of Immorally mediated damage within the central nervous system of AIDS patients
- 1 February 1989
- journal article
- research article
- Published by Wolters Kluwer Health in Neurology
- Vol. 39 (2) , 278
- https://doi.org/10.1212/wnl.39.2.278
Abstract
The pathogenesis of CNS damage by human immunodeficiency virus infection is unclear. Because there is little detectable virus within the CNS, we evaluated the role of the humoral immune system in mediating CNS tissue destruction. The paucity and nonspecific nature of immunoglobulin deposition rules against significant involvement of humorally mediated injury in the pathogenesis of AIDS encephalopathy.This publication has 5 references indexed in Scilit:
- Evidence for Early Central Nervous System Involvement in the Acquired Immunodeficiency Syndrome (AIDS) and Other Human Immunodeficiency Virus (HIV) InfectionsAnnals of Internal Medicine, 1987
- Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients.Proceedings of the National Academy of Sciences, 1986
- The AIDS dementia complex: II. NeuropathologyAnnals of Neurology, 1986
- The AIDS dementia complex: I. Clinical featuresAnnals of Neurology, 1986
- Intra-Blood–Brain-Barrier Synthesis of HTLV-III-Specific IgG in Patients with Neurologic Symptoms Associated with AIDS or AIDS-Related ComplexNew England Journal of Medicine, 1985