THE ASSAY OF ANDROSTERONE BY THE CHICK COMB WEIGHT METHOD AND THE RENAL EXCRETION OF ANDROGENS BY THE CEBUS MONKEY
- 1 November 1947
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 41 (5) , 335-339
- https://doi.org/10.1210/endo-41-5-335
Abstract
A linear relationship exists between the wt. of the comb of the baby chick and the logarithm of the dose of androsterone applied locally in oil soln. Groups of 11-20 birds received from 3.5-168 [gamma] of the hormone and it was found that the slopes of the straight lines differ significantly only for doses above 50 [gamma]. Following the steps of Bliss and Marks, this test was employed for assaying the androgenic potency of urinary extracts of 6 adult, [male] [male], South American monkeys of the genus Cebus, weighing 2.5-4.5 kg. The renal excretion of androgens by this primate was found very low, equivalent to 194 [plus or minus] 14 [gamma] of "androsterone"/l.Keywords
This publication has 3 references indexed in Scilit:
- DETAILED DESCRIPTION OF TECHNIQUE FOR ANDROGEN ASSAY BY THE CHICK COMB METHOD1Endocrinology, 1942
- A method of conducting a biological assay on a preparation giving repeated graded responses illustrated by the estimation of histamineThe Journal of Physiology, 1942
- EXCRETION OF ESTROGENIC AND ANDROGENIC SUBSTANCES BY FEMALE AND MALE CHIMPANZEES WITH KNOWN MATING BEHAVIOR RECORDS1Endocrinology, 1941