Induction of interferon synthesis by synthetic double-stranded polynucleotides
- 1 June 1968
- journal article
- research article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 2 (6) , 648-+
- https://doi.org/10.1128/jvi.2.6.648-650.1968
Abstract
Solutions of polyriboinosinic acid (rI) and polyribocytidylic acid (rC) polymerized upon mixing to form double-stranded rI:rC which prevented plaque formation in cultures of rabbit kidney cells infected with bovine vesicular stomatitis virus. The plaque inhibition was due to interferon induction.This publication has 5 references indexed in Scilit:
- Inducers of interferon and host resistance, IV. Double-stranded replicative form RNA (MS2-Ff-RNA) from E. coli infected with MS2 coliphage.Proceedings of the National Academy of Sciences, 1967
- Inducers of interferon and host resistance. II. Multistranded synthetic polynucleotide complexes.Proceedings of the National Academy of Sciences, 1967
- Inhibition of Sindbis Virus Plaque Formation by Extracts of Escherichia coliJournal of Bacteriology, 1966
- Physical and chemical characterization of the ordered complexes formed between polyinosinic acid, polycytidylic acid and their deoxyribo-analoguesJournal of Molecular Biology, 1965