Chromosomal organization of the amplified esterase B1 gene in organophosphate-resistant Culex pipiens quinquefasciatus Say (Diptera, Culicidae)
- 1 February 1990
- journal article
- research article
- Published by Canadian Science Publishing in Genome
- Vol. 33 (1) , 148-152
- https://doi.org/10.1139/g90-023
Abstract
In Culex pipiens quinquefasciatus from California, high resistance to organophosphorus insecticides is due to an increased production of the detoxifying esterase B1 resulting from a 250-fold amplification of the structural gene. The chromosomal organization of this amplified gene was studied by in situ hybridization techniques. Esterase B1 gene copies were found to be clustered on a single chromosome, tentatively identified as chromosome II.Key words: gene amplification, insecticide resistance, chromosomes, in situ hybridization, mosquitoes.This publication has 0 references indexed in Scilit: