Biosynthesis of proteins. 4. The effect of intravenous peptides on casein synthesis in a lactating goat

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Abstract
A partial acid hydrolysate of goat casein was fractionated into 2 groups of lysine peptides; one of these was injected into a lactating goat together with radioactive iysine. The casein synthesized during the 2 hours following injection was partially hy-drolyzed, and the distribution of radioactivity in the resultant peptide mixture was determined. The injection of lysine peptides did not alter the uniform distribution of C14-lysine between different peptides. Results indicate that peptides circulating in the blood cannot be used for casein synthesis without prior degradation to amino acids.