Developmental outcome of neonatal intensive care: what questions are we asking?

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Abstract
Recent neonatal intensive care outcome studies are asking more focused research questions and incorporating, at least implicitly, pathogenetic models. A few have grappled with the complex issues of health-related quality of life and functional outcomes and the many factors that affect these outcomes. The need to evaluate high-risk obstetrics is increasingly recognized. Studies of risk factors for neurodevelopmental outcomes provide valuable insights into mechanisms of and recovery from central nervous system injury. Ongoing study of the efficacy and effectiveness of interventions must continue amid concern about availability of family and developmental support for increasing numbers of survivors of high-risk obstetric and neonatal intensive care.