Apomorphine Revived: Fortified, Prolonged, and Improved Therapeutical Effect

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Abstract
An historical review is presented of the evolution of the clinical apomorphine treatment. Some of the results from the last 10 yr of psychopharmacological research led to the hypothesis that there exists a close relationship between abstinence and craving symptoms in drug and alcohol addicts, and that anxiety, depression and tremor symptoms in parkinsonism (and dementia senilis), are due to disturbances of the same, mainly dopaminergic, pathways in the CNS. By means of effective preparations for oral use, the synergistic effect of small amounts of apomorphine, L-dopa and decarboxylase inhibitor were used with considerable therapeutic effect.

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