Chiral synthesis of 3-substituted morpholines via serine enantiomers and reductions of 5-oxomorpholine-3-carboxylates
- 1 January 1985
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 12,p. 2577-2580
- https://doi.org/10.1039/p19850002577
Abstract
The chiral synthesis of 3-hydroxymethyl- and 3-carboxy-morpholines from serine enantiomers is described. Chemoselective and total reductions of 5-oxomorpholine-3-carboxylates are key synthetic steps.This publication has 2 references indexed in Scilit:
- Optical isomers of 2-(2-ethoxyphenoxymethyl)tetrahydro-1,4-oxazine (viloxazine) and related compoundsJournal of Medicinal Chemistry, 1976
- Die Synthese optisch aktiver N‐Monomethyl‐AminosäurenHelvetica Chimica Acta, 1962