Colonic bacterial proteases to IgA1 and sIgA in patients with ulcerative colitis.
Open Access
- 1 February 1987
- Vol. 28 (2) , 186-189
- https://doi.org/10.1136/gut.28.2.186
Abstract
The colonic faecal and mucosal associated bacterial populations of five patients with ulcerative colitis and four control patients were studied in detail to assess their ability to produce IgA1-proteases. A total of 330 bacterial strains were isolated from the patients with ulcerative colitis and IgA1-protease activity was unable to be reliably shown in any. It is therefore unlikely that such enzyme production by colonic bacteria plays a significant role in the pathogenesis of ulcerative colitis.This publication has 26 references indexed in Scilit:
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