Tin(II) chloride dihydrate–a mild reagent for the transformation of 6-nitro-Δ5-steroids to 5α-hydroxy-6-ketosteroids
- 1 January 1990
- journal article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 6,p. 498-499
- https://doi.org/10.1039/c39900000498
Abstract
Reaction of excess hydrated tin(II) chloride with 6-nitro-Δ5-steroids (1a–g) and (5) in tetrahydrofuran furnishes 5α-hydroxy-6-ketosteroids (2a–g) and (6) respectively, in good yields.Keywords
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