Utilization of L(+) Lactate in Patients with Liver Disease
- 1 January 1982
- journal article
- research article
- Published by S. Karger AG in Annals of Nutrition and Metabolism
- Vol. 26 (5) , 308-314
- https://doi.org/10.1159/000176579
Abstract
Clearance of intravenously infused sodium L(+) lactate was slower in 37 patients with liver disease (14.5 ± 0.9 ml (kg BW)-1min-1) than in 20 normal subjects (17.9 ± 1.1 ml (kg BW)-1min-1). This difference is statistically significant (2p < 0.0125). Impairment of L(+) lactate utilization was not related to the aetiology of the liver disease. Both increased production and decreased utilization of L(+) lactate were found in patients with secondary malignancy of the liver. Penetration of L(+) lactate into ascitic fluid was variable and estimates of L(+) lactate utilization may be unreliable if ascites is present.This publication has 2 references indexed in Scilit:
- Splanchnic removal of lactate and pyruvate during prolonged exercise in manJournal of Applied Physiology, 1966
- GLUCOSE SUPPLY BY LIVING HOST GLYCOLYSIS OF YOSHIDA ASCITES HEPATOMA IN VIVO1963