Morphological reaction in transplanted small intestines using immunogenetically defined rat strain combinations

1 June 1978

journal article
research article
Published by Springer Nature in Langenbecks Archives Of Surgery

Vol. 346 (2) , 119-127
https://doi.org/10.1007/bf01261398

Abstract

Summary From the inbred rat strains F344, LEW and Brown-Norway (BN), the following combinations were formed: syngeneic (LEW-LEW), weakly allogeneic (F344-LEW) and strongly allogeneic (BN-LEW). A small intestine segment was transplanted using the by-pass technique; after 10 days the graft was removed and histologically investigated. The strongest rejection was found in the lymphatic tissue and the epithelium of the small intestinal transplant. The immunogenetical difference is significant for the survival of the graft: the greater the immunogenetical difference between donor and host, the more severe the morphologically demonstrable rejection reaction.

Keywords

This publication has 20 references indexed in Scilit:

[Allogeneic small intestine transplantation in inbred rats. Transplantation technic and morphological findings].
1976
Allogene Dünndarmübertragung bei Inzuchtratten. Transplantationstechnik und morphologische Befunde
Published by Springer Nature ,1976
Absorption of carbohydrates and vitamins in the preserved and transplanted small intestine
The American Journal of Surgery, 1975
Small Bowel Preservation
Archives of Surgery, 1973
Lymphgefäßregeneration nach experimenteller heterotoper auto- und homologer Dünndarmtransplantation
Published by Springer Nature ,1972
Absorption Studies in Canine Jejunal Allografts
Annals of Surgery, 1971
Intestinal transplantation: Laboratory experience and report of a clinical case
The American Journal of Surgery, 1971
Transplantation of stomach, intestine, and pancreas: experimental and clinical observations.
1967
STRUCTURE + FUNCTION OF CANINE SMALL INTESTINE FOLLOWING TOTAL ABDOMINAL VAGOTOMY
1964
The Physiological Response of the Small Bowel of the Dog to Ischemia Including Prolonged in Vitro Preservation of the Bowel with Successful Replacement and Survival
Annals of Surgery, 1959