The sphingosine kinase 1/sphingosine‐1‐phosphate pathway mediates COX‐2 induction and PGE2production in response to TNF‐α
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Open Access
- 3 June 2003
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 17 (11) , 1411-1421
- https://doi.org/10.1096/fj.02-1038com
Abstract
In this study we addressed the role of sphingolipid metabolism in the inflammatory response. In a L929 fibroblast model, tumor necrosis factor-α (TNF) induced prostaglandin E2 (PGE2) production by 4 ...Keywords
Funding Information
- National Institutes of Health (CA87584, GM43825, GM62887)
- Norges Idrettshøgskole (NIH-HL 07260)
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