Stereochemistry of the enzymic 3-hydroxylation of 1,3-dihydro-2H-1,4-benzodiazepin-2-ones

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1 January 1973

journal article
research article
Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications

No. 19,p. 721-722
https://doi.org/10.1039/c39730000721

Abstract

The enzymic hydroxylation at C-3 of demethyldiazepam (1) and diazepam (2) proceeds through stereospecific removal of the pro-S hydrogen atom.

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