In Vitro Evaluation of a Semisynthetic Derivative of Gentamicin B (SCH 21420)
- 1 May 1978
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 13 (5) , 891-892
- https://doi.org/10.1128/aac.13.5.891
Abstract
The activities of Sch 21420 and amikacin were compared in vitro against 448 clinical bacterial isolates and against 82 gentamicin-resistant isolates of gram-negative bacilli. At 1 μg/ml, Sch 21420 was more active than amikacin against most Enterobacteriaceae but less active against Pseudomonas aeruginosa . Activity of these antibiotics against gentamicin-resistant organisms varied according to the species examined.Keywords
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