Influence of Copper on Stearic Acid Desaturation and Fatty Acid Composition in the Pig

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Abstract
The effect of feeding a diet supplemented with copper sulfate to provide 250 ppm of supplemental copper was studied with respect to fatty acid composition and stearic acid desaturation in the liver and adipose tissues of pigs. The oleic/stearic acid ratio of outer subcutaneous fat and perirenal fat was significantly greater in fat from the copper supplemented pigs than in the control pigs. The specific activity of the liver stearic acid desaturase system was also significantly greater in the copper supplemented pigs than in the controls. In vitro studies with various copper sulfate concentrations showed an activation of the liver stearic acid desaturase system at copper concentrations normally found in the livers of pigs fed 250 ppm of supplementary copper from copper sulfate. Therefore, the increased degree of unsaturation in lipids from pigs fed supplementary copper can be at least partially related to copper activation of the stearic acid desaturase system in the liver. Copyright © 1973. American Society of Animal Science . Copyright 1973 by American Society of Animal Science.

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