THE USE OF MONOCLONAL-ANTIBODIES FOR THE ANTIGENIC ANALYSIS OF INFLUENZA-A VIRUSES

  • 1 January 1985
    • journal article
    • research article
    • Vol. 63  (2) , 265-271
Abstract
Monoclonal antibodies provide useful additional information for the antigenic analysis of influenza A viruses of the H3N2 and H1N1 subtypes. They are particularly useful in the interpandemic period when multiple variants circulate concurrently. Apparently heterogeneous isolates can be placed in fairly clear-cut groups on the basis of their reactivity with certain monoclonal antibody preparations. Variants reacting with the least number of monoclones are probably the most different antigenically from the fully reactive strains.