GLOBAL SURVEILLANCE OF ANTIBIOTIC SENSITIVITY OF VIBRIO-CHOLERAE

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  • 1 January 1976
    • journal article
    • research article
    • Vol. 54  (2) , 181-185
Abstract
Strains of V. cholerae, 1156 from various parts of the world, were examined by standardized antibiotic sensitivity tests in 1 center, to determine the global incidence of antibiotic resistance in this organism and to assess the extent to which differences in methods of sensitivity testing might be responsible for discrepancies in the reported incidence of resistant strains. Of the strains examined, 1127 were fully sensitive to ampicillin, chloramphenicol, tetracycline, furazolidone and 3 different sulfonamides, 27 showed stable and reproducible resistance to 1 or more of these agents and 2 contained a minority of cells with unstable, presumably plasmid-borne, resistance to chloramphenicol. Unstable resistance to antibiotics may be common in V. cholerae but rarely recognized and may account for some of the discrepancies in the reported incidence of resistant strains.