PURIFICATION AND PROPERTIES OF 2 FORMS OF SOLUBLE 3'-5'-AMP-DEPENDENT PROTEIN-KINASE FROM THE RABBIT MYOCARDIUM

  • 1 January 1979
    • journal article
    • research article
    • Vol. 51  (2) , 165-169
Abstract
Two forms of cyclic[c]AMP-dependent protein kinase were purified from the rabbit myocardium. The concentrations of cAMP-necessary for maximum stimulation of concentration to a greater extent. The apparent Km for ATP for the both forms in the presence of cAMP is 8.3 .cntdot. 10-6 M. For enzyme form I the Km for histone H1 was 0.43 mg/ml and for form II.sbd.0.67 mg/ml.

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