Nitrosation under alkaline conditions
- 1 January 1976
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Chemical Communications
- No. 21,p. 877-878
- https://doi.org/10.1039/c39760000877
Abstract
Both gaseous N2O3 and N2O4, but not NO, are shown to effect the nitrosation of primary and secondary amines in neutral and alkaline aqueous solutions; the reaction rates are rapid, insensitive to amine basicity and are not inhibited by HO–, which is consistent with radical pathways involving NO2 and NO, and therefore carcinogenic N-nitrosamines may form under a much wider range of experimental conditions than hitherto suspected.This publication has 0 references indexed in Scilit: