Metformin Transport by Renal Basolateral Organic Cation Transporter hOCT2
- 24 February 2005
- journal article
- research article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 22 (2) , 255-259
- https://doi.org/10.1007/s11095-004-1193-3
Abstract
Metformin, an antihyperglycemic agent, is eliminated by tubular secretion in addition to glomerular filtration in the human kidney. This study was performed to characterize metformin transport by human organic cation transporter 2 (hOCT2), the most abundant organic cation transporter in the basolateral membranes of the human kidney.Keywords
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