Phenothiazine‐induced systemic lupus erythematosus with superior vena cava syndrome: case report and review of the literature

Abstract
Phenothiazine‐induced lupus with circulating anticoagulant (CAC) has been reported infrequently, and is rarely associated with significant symptoms. We describe a patient who we suspect had perphenazine‐induced lupus erythematosus with CAC. She had recurrent episodes of venous thrombosis and ultimately developed superior vena cava syndrome. The relationships among phenothiazine‐induced lupus, CAC, and thrombosis are discussed.