Cyclosporin A-induced changes in endogenous metabolites in rat urine: a metabonomic investigation using high field NMR spectroscopy, HPLC-TOF/MS and chemometrics
- 6 May 2004
- journal article
- research article
- Published by Elsevier in Journal of Pharmaceutical and Biomedical Analysis
- Vol. 35 (3) , 599-608
- https://doi.org/10.1016/j.jpba.2004.02.013
Abstract
No abstract availableKeywords
This publication has 16 references indexed in Scilit:
- Metabolite profiling in rat urine by liquid chromatography/electrospray ion trap mass spectrometry. Application to the study of heavy metal toxicityRapid Communications in Mass Spectrometry, 2003
- Screening of Biomarkers in Rat Urine Using LC/Electrospray Ionization-MS and Two-Way Data AnalysisAnalytical Chemistry, 2003
- Physiological variation in metabolic phenotyping and functional genomic studies: use of orthogonal signal correction and PLS‐DAFEBS Letters, 2002
- Metabonomics: the use of electrospray mass spectrometry coupled to reversed‐phase liquid chromatography shows potential for the screening of rat urine in drug developmentRapid Communications in Mass Spectrometry, 2002
- An NMR‐based metabonomic approach to investigate the biochemical consequences of genetic strain differences: application to the C57BL10J and Alpk:ApfCD mouseFEBS Letters, 2000
- Metabonomics: Evaluation of Nuclear Magnetic Resonance (NMR) and Pattern Recognition Technology for Rapid in Vivo Screening of Liver and Kidney ToxicantsToxicological Sciences, 2000
- A1H NMR spectroscopic study of the biochemical effects of ifosfamide in the rat: evaluation of potential biomarkersBiomarkers, 2000
- Nuclear Magnetic Resonance Spectroscopic and Principal Components Analysis Investigations into Biochemical Effects of Three Model HepatotoxinsChemical Research in Toxicology, 1998
- Nuclear Magnetic Resonance and High-Performance Liquid Chromatography-Nuclear Magnetic Resonance Studies on the Toxicity and Metabolism of IfosfamideTherapeutic Drug Monitoring, 1996
- Use of urinary taurine and creatine as biomarkers of organ dysfunction and metabolic perturbationsComparative Clinical Pathology, 1995