cDNA gene expression profile homology of antioxidants and their antiapoptotic and proapoptotic activities in human neuroblastoma cells
Open Access
- 5 March 2003
- journal article
- fj express-summaries
- Published by Wiley in The FASEB Journal
- Vol. 17 (8) , 1-26
- https://doi.org/10.1096/fj.02-0712fje
Abstract
Antioxidants have concentration-dependent neuroprotective and proapoptotic activities in models of Parkinson's disease. The aim of our study was to determine gene-protein pathways of the antioxidants...Keywords
Funding Information
- National Parkinson Foundation
- Technion-Israel Institute of Technology
This publication has 49 references indexed in Scilit:
- Iron chelating, antioxidant and cytoprotective properties of dopamine receptor agonist; apomorphinePublished by Springer Nature ,2000
- Apomorphine enantiomers protect cultured pheochromocytoma (PC12) cells from oxidative stress induced by H2O2 and 6‐hydroxydopamineMovement Disorders, 1998
- MPP+Produces Progressive Neuronal Degeneration Which Is Mediated by Oxidative StressExperimental Neurology, 1997
- DOPAMINE-INDUCED APOPTOSIS IN HUMAN NEURONAL CELLS: INHIBITION BY NUCLEIC ACIDS ANTISENSE TO THE DOPAMINE TRANSPORTERNeuroscience, 1996
- Induction of apoptosis in catecholaminergic PC12 cells by L-DOPA. Implications for the treatment of Parkinson's disease.Journal of Clinical Investigation, 1995
- Oxidative stress: Free radical production in neural degenerationPharmacology & Therapeutics, 1994
- Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosisNeuroscience, 1994
- Reactive Oxygen Species and the Central Nervous SystemJournal of Neurochemistry, 1992
- Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian BrainsJournal of Neurochemistry, 1989
- A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.Proceedings of the National Academy of Sciences, 1983