CARDIAC EFFECTS OF HALOTHANE AND ADRENALINE IN HARE-LIP AND CLEFT-PALATE SURGERY

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Abstract
Forty-five infants and young children undergoing hare-lip and cleft-palate surgery were anaesthetized with halothane, ether, nitrous oxide and oxygen. Lignocaine 2 per cent with adrenaline as a 1:80,000 solution was infiltrated around the arteries at the point of entry to the lip and palate and the pulse rate, systolic blood pressure and electro-cardiogram monitored. Apart from a slight increase in pulse rate, no significant changes could be detected in systolic blood pressure or in the electrocardiogram. It is suggested that in this age group a mean dose of adrenaline of 3.5 mg/kg in infants and 2.5 mg/kg in children up to 2 years of age may be safely used as an infiltration injection in the presence of small concentrations of halothane.

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