Stability constants and 1H relaxation effects of ternary complexes formed between gd‐dtpa, gd‐dtpa‐bma, gd‐dota, and gd‐edta and citrate, phosphate, and carbonate ions
- 1 July 1997
- journal article
- other
- Published by Wiley in Magnetic Resonance in Medicine
- Vol. 38 (1) , 146-150
- https://doi.org/10.1002/mrm.1910380120
Abstract
Formation of ternary complexes between Gd‐DTPA, Gd‐DTPA‐BMA, and Gd‐DOTA, used as contrast enhancement agents in MRI and the endogenously available carbonate and phosphate ions, has been demonstrated. The extent of ternary complex formation and its effect on the proton relaxation, measured at 9 MHz, rates is negligible at around pH X) (X = CO32‐, Cit3‐) results in a significant decrease in the proton relaxation rates under physiological conditions.Keywords
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