Inhibition of cholesterol biosynthesis in Chinese hamster ovary cells by 4,4,10 beta-trimethyl-trans-decal-3 beta-ol. A specific 2,3-oxidosqualene cyclase inhibitor.
Open Access
- 1 November 1979
- journal article
- research article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 254 (22) , 11258-11263
- https://doi.org/10.1016/s0021-9258(19)86479-7
Abstract
No abstract availableThis publication has 27 references indexed in Scilit:
- Biological Activity of Some Oxygenated SterolsScience, 1978
- A novel inhibitor of steroid biosynthesisJournal of the American Chemical Society, 1978
- Effect of triparanol and 3β-(β-dimethyl-aminoethoxy)-androst-5-en-17-one on growth and non-saponifiable lipids of saccharomyces cerevisiaeBiochemical Pharmacology, 1976
- Receptor-Mediated Control of Cholesterol MetabolismScience, 1976
- Regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured swine aortic smooth muscle cells by plasma lipoproteinsBiochemistry, 1975
- Micro assay for 3-hdyroxy-3-methylglutaryl-CoA reductase in rat liver and in L-cell fibroblastsBiochimica et Biophysica Acta (BBA) - Enzymology, 1974
- Comparative properties of 2,3-oxidosqualene-lanosterol cyclase from yeast and liverBiochimica et Biophysica Acta (BBA) - Enzymology, 1970
- Formation of sterols by the action of 2,3-oxidosqualene-sterol cyclase on the factitious substrates, 2,3,: 22,23-dioxidosqualene and 2,3-oxido-22,23-dihydrosqualeneJournal of the American Chemical Society, 1967
- 2,3-Iminosqualene, a potent inhibitor of the enzymic cyclization of 2,3-oxidosqualene to sterolsJournal of the American Chemical Society, 1967
- THE DISTRIBUTION AND CHEMICAL COMPOSITION OF ULTRACENTRIFUGALLY SEPARATED LIPOPROTEINS IN HUMAN SERUMJournal of Clinical Investigation, 1955