Suppression of T cell responses through competition for T cell growth factor (interleukin 2)
- 1 January 1982
- journal article
- research article
- Published by Wiley in European Journal of Immunology
- Vol. 12 (3) , 247-249
- https://doi.org/10.1002/eji.1830120315
Abstract
Addition of activated T cells or of cells from a cytotoxic T cell clone to mixed leukocyte cultures abolished the generation of cytolytic activity in these cultures. The cytolytic T cell response is completely restored if T cell growth factor (interleukin 2) is added, indicating that the suppression is due to absorption or consumption of IL2 by the added cells.This publication has 14 references indexed in Scilit:
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