Enhancement of propoxyphene-induced analgesia by doxepin
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Psychopharmacology
- Vol. 51 (2) , 213-215
- https://doi.org/10.1007/bf00431744
Abstract
The activity of the centrally acting analgesic, propoxyphene, either alone or combined with the tricyclic antidepressant, doxepin, has been studied. Doses of doxepin, in themselves lacking any analgesic effect, remarkably enhanced the analgesic activity of propoxyphene, either by the oral or intraperitoneal route. On the other hand, oral toxicity data prove that doxepin does not alter significantly propoxyphene acute toxicity.This publication has 3 references indexed in Scilit:
- Drug Interactions with Clomipramine (Anafranil)Journal of International Medical Research, 1973
- Clomipramine (Anafranil) in the Treatment of Pain, Enuresis and Anorexia NervosaJournal of International Medical Research, 1973
- Nouvelle recherche sur le mécanisme d'action de quelques analgésiques centrauxPsychopharmacology, 1966