THE MALE HORMONE

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Abstract
The urine of young men contains a hormone which induces comb growth in capons when a properly prepared extract of such urine is injected. Extracts from testicles, when injected, also give definite, but less marked effects. The difference may depend on the amount of material used. Administration per os also has some effect, but much less pronounced and less constant than when the extract is injected. The [male] and [female] hormones show marked similarity in chemical properties. Both may be extracted with chloroform; both form alkaline salts; both are found in the fatty acid fraction; and the methods of purification so far adopted apply to both hormones.

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